"Grey's Anatomy" is a clever title with layers of meaning, giving us a hint about what the show is all about. At the surface level, it refers to the main character, Meredith Grey, and explores her life (her anatomy, if you wish) and her relationships with her colleagues and patients. On a deeper level though, the title "Grey's Anatomy" is also a direct reference to the classic medical textbook "Gray's Anatomy", which was written by Henry Gray back in 1858. This medical book is widely used in medical schools worldwide, as it provides detailed descriptions and images of the human body (anatomy). So, essentially, the show's title is a pun combining these two elements - Meredith Grey's life and the field of medical study, signalling the show's dual focus on personal drama and the practice of medicine. Furthermore, it also subtly indicates the struggles, experiences, growth and lessons (personal and professional) that the characters experience, just like the complex anatomy of the human body. This multifaceted title has set the tone for the show's content, thereby making "Grey's Anatomy" instantly recognizable and memorable. It also establishes the expectation that the show will delve into medical intricacies and the personal lives of the doctors, the same way "Gray's Anatomy" dives into the intricacies of the human body, while highlighting Dr. Grey's journey as a central point.